The following list of substances may interact with each other in the body because they are all metabolized by the enzyme CYP3A4
(aka “cytochrome p450 3A4”). Various kinds of interactions can occur, depending upon the substances involved. These can result
in changes in bioavailability, half-life, and the levels of these and other substances in the body.
GENERIC NAME (BRAND NAME)
- Alprazolam (Xanax)
- Amiodarone (Cordarone)
- Amitriptyline (Elavil)
- Astemizole (Hismanal)
- Budesonide (Rhinocort)
- Bupropion (Wellbutrin)
- Buspirone (BuSpar)
- Caffeine
- Carbamazepine (Tegretol)
- Cerivastatin (Baycol)
- Cisapride (Propulsid)
- Clarithromycin (Biaxin)
- Clomipramine (Anafranil)
- Clonazepam (Klonopin)
- Codeine
- Cyclosporine (Sandimmune)
- Dexamethasone
- Dextromethorphan
- DHEA
- Diazepam (Valium)
- Diltiazem (Cardizem)
- Disopyramide (Norpace)
- Donepezil (Aricept)
- Doxycycline (Vibramycin)
- Erythromycin
- Estradiol (Estrace)
- Ethinylestradiol (Estinyl)
- Felodipine (Plendil)
- Fluoxetine (Prozac)
- Imipramine (Tofranil)
- Indinavir
- Itraconazole
- Ketoconazole
- Lansoprazole (Prevacid)
- Lidocaine (Xylocaine)
- Loratadine (Claritin)
- Lovastatin (Mevacor)
- Midazolam (Versed)
- Nefazodone (Serzone)
- Nelfinavir
- Nicardipine (Cardene)
- Nifedipine (Procardia)
- Nisoldipine (Sular)
- Norethindrone (Micronor)
- Omeprazole (Prilosec)
- Ondansetron (Zofran)
- Orphenadrine (Norflex)
- Paroxetine (Paxil)
- Progesterone
- Propafenone (Rhythmol)
- Quetiapine (Seroquel)
- Quinidine
- Rifampin (Rifadin)
- Ritonavir
- Sertraline (Zoloft)
- Sibutramine (Meridia)
- Sildenafil (Viagra)
- Simvastatin (Zocor)
- Tacrolimus (Prograf)
- Tamoxifen (Nolvadex)
- Terfenadine (Seldane)
- Testosterone
- Theophylline
- Trazodone (Desyrel)
- Triazolam (Halcion)
- Troleandmycin
- Venlafaxine (Effexor)
- Verapamil (Calan)
- Vinblastine (Velban)
- (R)-Warfarin
- Zolpidem (Ambien)
